Diaper Rash Cream Diaper Rash Cream

Diaper Rash Cream


Diaper Rash Cream


  • Full Size: 3 fl oz
  • Travel Size: 1 fl oz

A fragrance-free Diaper Rash Cream that creates a protective moisture barrier for your little one, helping to seal out wetness and soothe the chafed, red skin. Petrolatum-free, lanolin-free, and vegan, it’s gentle and safe for the most sensitive skin, and helps prevent diaper irritation before it starts. Bonus: our moisture-rich formula glides onto skin easily—and wipes off when you need it to.


Clean ingredients you can trust

Diaper Rash Cream soothes skin and prevents diaper rash

14% non-nano zinc oxide creates a safe, gentle, and effective barrier to protect against and soothe the red, chafed skin of diaper rash.


Diaper Rash Cream deeply calms and moisturizes

Bisabolol, a plant-derived ingredient famous for its anti-inflammatory properties, nourishes and comforts baby’s most sensitive skin.


Baby Diaper Rash Cream replenishes what they’re born with 

Our sugarcane-derived squalane is clinically proven to help balance the microbiome, which supports the moisture barrier for more resilient, healthy-looking skin.

Full list of ingredients

Active Ingredient: 

Zinc Oxide 14%: Non-nano natural mineral creates a gentle barrier to protect against and soothe diaper rash

Inactive ingredients: 

Glycerin: Plant-derived moisture attractor that helps our formula glide on easily

Squalane: 100% sugarcane-derived sustainable ingredient clinically proven to help balance the microbiome, which helps support the moisture barrier for more resilient, healthy-looking skin

Butyrospermum Parkii (Shea) Butter: Plant-derived moisturizer rich in antioxidants

Jojoba Esters: Hydrating, plant-derived skin softeners

Euterpe Oleracea (Açaí Berry) Sterols: Antioxidant-rich superfruit that helps calm skin and retain moisture

Sorbitan Olivate: Plant-derived skin softener

Polyglyceryl-2 Dipolyhydroxystearate: Plant-derived fatty acid esters that stabilize our formula

Linoleic Acid: Plant-derived antioxidant-rich fatty acid that helps lock in moisture

Oleic Acid: Plant-derived essential fatty acid that helps calm and moisturize skin 

Linolenic Acid: Plant-derived essential fatty acid that helps calm and moisturize skin

Bisabolol: Sugarcane-derived ingredient renowned for its anti-inflammatory and skin-calming properties

Tocopherol (Vitamin E): Antioxidant vitamin that helps improve skin suppleness

1,2-Hexanediol: Safe preservative and moisture-attracting humectant

Caprylyl Glycol: Plant-derived ingredient that boosts preservative effectiveness 

Drug Facts

Active ingredient                                  Purpose

Zinc oxide 14%............................ Skin protectant


• helps treat and prevent diaper rash

• protects chafed skin due to diaper rash and helps seal out wetness


For external use only
When using this product:

  • do not get into eyes 

Stop use and ask a doctor if

  • condition worsens
  • symptoms last more than 7 days or clear up and occur again within a few days

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.


  • change wet and soiled diapers promptly
  • cleanse the diaper area
  • allow to dry
  • apply cream liberally as often as necessary, with each diaper change, and especially at bedtime or any time when exposure to wet diapers may be prolonged
Learn more about our ingredients

Baby Diaper Rash Cream is soft on skin, strict on standards

All Pipette products are created with the support of biologists, dermatologists, and pediatricians, and are rigorously tested to ensure their safety. All formulas are hypoallergenic, free of synthetic fragrances, cruelty-free, and vegan. Gentle enough for even the most sensitive skin, our Diaper Rash Cream can be used any time the diaper area is irritated, red, or in need of extra attention.

How to use

At each diaper change, apply liberally to clean, dry skin. Be sure to pay special attention to skin at bedtime or any time when baby’s exposure to wet diapers might be prolonged. 

  • Pediatrician Backed
  • Safe for Sensitive Skin
Clinical Results
  • 100% of parents said the Diaper Rash Cream was effective at preventing diaper rashes.*

  • 100% of parents said if a rash was already present, the Diaper Rash Cream helped calm the irritation.*

    • 100% said the baby rash cream helped keep baby's bottom dry in between diaper changes.*
    • 100% said the Diaper Rash Cream helped minimize chafing or irritation on baby's diaper area.*

*Based on a 14-day consumer use study of 32 children, ages 6 months - 3 years, after 14 days of use. 

All your diaper rash FAQs, answered

Diapering: it's a dirty job, but hey, someone's gotta do it (and that someone is...you.) We asked pediatric dermatologist Peter Lio, MD, how to keep your kiddo's most delicate skin clean, cared for, and rash-free.

Read More

Customer Reviews

Customer Reviews
4.8 Based on 20 Reviews
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Filter Reviews:
Maggie V.
United States United States
Diaper rash defender

Love this product! My husband has very sensitive skin so was worried about our newborn following in his dad’s footsteps. I found Pipette on EWG, and ordered a starter kit of supplies. The diaper rash cream has treated minor rash but more importantly kept it away, great barrier cream. No allergic reactions at all and baby’s skin looks brand new. I highly recommend.

Regina F.
United States United States
Very gentle rash cream

Super gentle on baby's bottom

Allison W.
United States United States
Perfect for more than just a baby’s bottom

This diaper cream is so much better than any other diaper cream I’ve ever used. It hasn’t got that weird chalky texture most of them have. It’s providing that barrier but also feels nourishing.

Lisa C.
United States United States
So far so good

We’ve been using the cream on some new diaper rash, I’m assuming is coming as my son is eating more solids. So far it’s working well.

Callie S.
United States United States

We had tried multiple diaper rash creams and nothing worked until this! It cleared up his poor red bum in less than a day! This is the only one I’ll use from now on!

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Caring for their skin and the world they’ll grow up in

Pipette is committed to caring for more than babies’ skin. From ingredients to packaging, our products are made as sustainably and ethically as possible